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Table 1 Cytotoxic T-cell lymphocyte predicted epitopes of selected proteins based on antigenicity, toxicity, and immunogenicity

From: Immunoinformatics approach for multi-epitope vaccine design against structural proteins and ORF1a polyprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)

Protein

Peptide

Length

Antigenicitya

Toxicityb

Immunogenicityc

S

QLTPTWRVY

9 mer

1.2119

Non-toxic

0.31555

VLPFNDGVY

9 mer

0.4642

Non-toxic

0.1815

WTAGAAAYY

9 mer

0.6306

Non-toxic

0.15259

CNDPFLGVY

9 mer

0.4295

Non-toxic

0.15232

M

AGDSGFAAY

9 mer

0.9095

Non-toxic

0.03981

N

LSPRWYFYY

9 mer

1.2832

Non-toxic

0.35734

DLSPRWYFY

9 mer

1.7645

Non-toxic

0.25933

ORF1a

VSDIDITFL

9 mer

2.2906

Non-toxic

0.38916

TLRVEAFEY

9 mer

0.4509

Non-toxic

0.34997

HVGEIPVAY

9 mer

0.6413

Non-toxic

0.28861

STNVTIATY

9 mer

0.7143

Non-toxic

0.25822

LVSDIDITF

9 mer

1.7830

Non-toxic

0.2541

NGDVVAIDY

9 mer

0.6625

Non-toxic

0.25105

VVDYGARFY

9 mer

0.4908

Non-toxic

0.18539

GTDPYEDFQ

9 mer

0.5315

Non-toxic

0.17381

VTNNTFTLK

9 mer

0.7146

Non-toxic

0.16567

ETSWQTGDF

9 mer

1.3140

Non-toxic

0.13449

FMGRIRSVY

9 mer

0.5212

Non-toxic

0.1259

VVVNAANVY

9 mer

0.4078

Non-toxic

0.10048

  1. aAntigenicity threshold = 0.4
  2. bToxicity threshold = 0.5
  3. cRank percentile \(\le\) 1.0
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Tropical Diseases, Travel Medicine and Vaccines

ISSN: 2055-0936

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