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Table 2 Helper T-cell lymphocyte predicted epitopes of selected proteins based on antigenicity and IFN-γ response

From: Immunoinformatics approach for multi-epitope vaccine design against structural proteins and ORF1a polyprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)

Protein

Peptide

Length

Antigenicitya

IFN-gamma

S

TRFASVYAWNRKRIS

15 mer

0.4963

0.7315567

FQTLLALHRSYLTPG

15 mer

0.5789

0.26071055

QPYRVVVLSFELLHA

15 mer

0.9109

0.60855322

M

SRTLSYYKLGASQRV

15 mer

0.5731

0.09462399

LVGLMWLSYFIASFR

15 mer

0.5535

0.20134879

ORF1a

VSTQEFRYMNSQGLL

15 mer

0.4972

0.97632046

AALGVLMSNLGMPSY

15 mer

0.8521

0.11429986

TLNGLWLDDVVYCPR

15 mer

0.4558

0.04915351

AYESLRPDTRYVLMD

15 mer

0.5553

0.30777655

SAGIFGADPIHSLRV

15 mer

0.5839

0.24837266

MFTPLVPFWITIAYI

15 mer

0.6806

0.1415124

  1. aAntigenicity threshold = 0.4
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Tropical Diseases, Travel Medicine and Vaccines

ISSN: 2055-0936

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