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Table 4 Seroconversion and Seroprotection Rate on Day 30 post-vaccination (PPS)

From: A post-marketing study to evaluate the safety and immunogenicity of a quadrivalent influenza split-virion vaccine in elderly people aged 60 years and older

Subtype

N

Seroconversion

Seroprotection

n

%

n

%

H1N1

348

305

87.64(83.72 ~ 90.91)

327

93.97(90.92 ~ 96.23)

H3N2

348

263

75.57(70.71 ~ 80.00)

343

98.56(96.68 ~ 99.53)

BV

348

255

73.28(68.30 ~ 77.85)

276

79.31(74.67 ~ 83.44)

BY

348

274

78.74(74.06 ~ 82.92)

332

95.40(92.64 ~ 97.35)

  1. Analyzed with titer detected by hemagglutination inhibition assay
  2. N: subject number of analyzing set as denominator;
  3. n: number of subjects whose detection result of corresponding subtype meet seroconversion/seroprotection standard;
  4. %: incidences of subjects whose detection result of corresponding subtype meet seroconversion/seroprotection standard
  5. Seroprotection is defined as hemagglutination inhibition (HI) antibody titer ≥ 1:40
  6. Seroconversion is defined as HI titer post-vaccination changed to ≥ 1:40 from baseline < 1:10 or ≥ 4-fold increase in HI titer post-vaccination from baseline ≥ 1:10